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风湿病中以类风湿性关节炎(RA)及系统性红斑性狼疮(SLE)最为多见,其发病年龄多于20～40岁之间,亦和妇女妊娠及哺乳年龄相吻合。目前治疗风湿病的药物已超过100种,主要包括非类固醇抗炎药、类固醇激素及免疫调节剂三大类。抗风湿药物对孕妇胎儿的影响,以及其对哺乳期婴儿有否不良作用,均为临床上十分关切的问题。本文结合文献综述如下。非类固醇抗炎药非类固醇抗炎药包括水杨酸类及非水杨酸两大类,小剂量阿司匹林具有缓解疼痛但无明显抗炎作
Rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE) is the most common, the onset of age more than 20 to 40 years old, but also with women’s pregnancy and breastfeeding age coincide. The current treatment of rheumatism drugs have more than 100 kinds, including non-steroidal anti-inflammatory drugs, steroid hormones and immunomodulators three categories. The impact of anti-rheumatic drugs on pregnant women’s fetuses and their adverse effects on lactating infants are all clinically significant issues. This article combines the literature is summarized as follows. Non-steroidal anti-inflammatory drugs Non-steroidal anti-inflammatory drugs include salicylic acid and non-salicylic acid two categories, low-dose aspirin with pain relief but no significant anti-inflammatory