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目的：探讨针对性的护理措施对围术期乳腺癌根治术患者的影响。方法以30例围术期乳腺癌根治术患者作为研究对象，分为观察组和对照组，每组各15例，对照组给予传统护理模式，观察组给予针对性护理。比较两组患者围术期并发症发生率及术后心理状况。结果对照组患者术后并发症发生率为33.33%，实验组为20%，两组间存在显著的差异(<0.05)；实验组患者术后SDS、SAS评分显著低于手术前和对照组手术后(<0.05)。结论对围术期乳腺癌患者进行针对性的护理措施，能有效缓解患者的焦虑、抑郁情绪反应，减少术后并发症发生率，促进疾病的预后。,Objective To explore the ef ect of targeted nursing measures in the perioperative period of radical mastectomy patients. Methods 30 cases of perioperative period of radical mastectomy patients as the research object, divided into observation group and control group, 15 cases in each group.The control group was given traditional nursing mode, the observation group were given targeted nursing. Comparison with incidence rate of complications and SDS, SAS score between two groups. Results The incidence rate of complications was 33.33%in the patients, the experimental group was 20%, there was significant dif erence between two groups ( <0.05);SDS, SAS score of experimental group of patients after operation was significantly lower than that in control group before operation and after operation ( <0.05). Conclusion The perioperative radical mastectomy patients with targeted nursing measures, can ef ectively relieve the patient’s anxiety, depression, reduce the incidence of postoperative complications and promote the prognosis of the disease.