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选取急性心肌梗死（ＡＭＩ）患者３１例，并设正常对照组。采用时域法和频域法研究ＡＭＩ溶栓治疗后心率变异性（ＨＲＶ）的改变。其结果显示：在ＡＭＩ再通组，其ＳＤＮＮ为１０８．１４±２８．４０ｍｓ，高于未通组的６２．６７±２６．１２ｍｓ（Ｐ＜０．０１）但低于对照组的１２８．４７±３５．６１ｍｓ（Ｐ＜０．０５）；其高频面积为２８４．８２±２７６．４５，大于未通组的（１３５．６８±１１７．８２ｂｐｍ２／Ｈｚ，Ｐ＜０．０５）但小于对照组的（６９４．３５±５４０．１１ｂｐｍ２／Ｈｚ，Ｐ＜０．０１）；其低频面积／高频面积为０．９３±０．７１，小于未通组的１．７４±１．０７（Ｐ＜０．０５），但大于对照组的０．５３±０．６１（Ｐ＜０．０１）；其低频面积虽大于未通组和小于对照组，但无统计学意义。本结果表明，ＡＭＩ后ＨＲＶ变小，其迷走神经活性下降，交感神经作用相对增强；溶栓再通后的ＨＲＶ增大，其迷走神经兴奋性增高，交感神经作用减弱。故成功的溶栓治疗对改善ＡＭＩ后自主神经系统功能失衡和减少由此引起的致命性心律失常等事件的发生有积极意义
Thirty-one patients with acute myocardial infarction (AMI) were selected and normal control group was established. The changes of heart rate variability (HRV) after AMI thrombolysis were studied by time-domain and frequency-domain methods. The results showed that in the AMI recanalization group, the SDNN was 108.14 ± 28.40 ms, which was higher than that of the non-recurrent group (62.67 ± 26.12 ms, P <0.01) but lower than that of the control group ± 35.61ms (P <0.05). The high-frequency area was 284.82 ± 276.45, which was significantly higher than that of the control group (135.68 ± 117.82bpm2 / Hz, P <0.05) Group (694.35 ± 540.11bpm2 / Hz, P <0.01). The area of low-frequency area / high-frequency area was 0.93 ± 0.71, <0.05), but higher than that of the control group (0.53 ± 0.61, P <0.01). Although the low-frequency area was larger than that of the control group, it was not statistically significant. The results show that, after AMI, HRV becomes smaller, the vagus nerve activity decreased, the role of sympathetic enhancement; thrombolytic recanalization increased HRV, the vagus nerve excitability increased, the role of sympathetic weakened. Successful thrombolytic therapy is therefore instructive in improving the dysfunctional autonomic nervous system after AMI and in reducing the incidence of fatal arrhythmias