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目的探讨时间-空间标记反转脉冲(Time-SLIP)非对比增强成像技术对正常肾动脉主干和分支显示的可重复性。方法 36名健康志愿者(男16名、女20名,平均年龄21.9岁)均行2次1.5 T Time-SLIP非对比增强肾动脉检查,前后间隔时间约为1~2周。记录前后2次血管-肾脏信号比(VKR)、肾动脉分支级数、图像质量评分、肾动脉主干直径与面积等五个参数,使用Bland-Altman法、测量者组内相关系数(ICC)和测量者间ICC评价可重复性。结果 2名测察者肾动脉分级的ICC分别为0.820和0.908。肾动脉第一段(动脉主干)图像质量评分测量者ICC和测量者间ICC均为1,第二段(肾门区动脉)和第三段(肾实质内动脉)图像质量评分ICC介于0.768~1之间,测量者间ICC介于0.864~0.969之间。双侧肾动脉主干直径和面积的95%LOA介于2.8%~5.6%之间,最小ICC值为0.795,2名测察者间的最小ICC值为0.839。两次检查VKR的95%LOA分别为75%和72.2%,测量者ICC分别为0.510和0.577。结论 Time-SLIP非对比增强成像技术对正常肾动脉主干及其分支的显示具有很高可重复性,在肾动脉病变、肾移植前筛查、肾移植后疗效评估和随访等方面具有重要的意义。
Objective To investigate the repeatability of the display of the trunk and branches of normal renal arteries by Time-SLIP contrast-enhanced imaging. Methods Twenty-six healthy volunteers (16 males and 20 females, mean age 21.9 years) underwent 1.5 T Time-SLIP non-contrast enhanced renal artery examinations. The anteroposterior interval was about 1-2 weeks. Five parameters of VKR, branch of renal artery, image quality score, diameter and area of renal artery trunk were recorded before and after recording. Bland-Altman method, correlation coefficient (ICC) Interobserver ICC evaluates repeatability. Results The ICC of two investigators’ renal artery grading were 0.820 and 0.908, respectively. The ICC of the first segment of the renal artery (arterial trunk) and ICC of the measurers were both 1, and the second segment (renal artery) and the third segment (renal parenchymal artery) had an ICC of 0.768 ~ 1 between the ICC measurement between 0.864 ~ 0.969. The 95% LOA of the diameter and area of the bilateral renal arteries was between 2.8% and 5.6%, the minimum ICC was 0.795, and the minimum ICC between the two investigators was 0.839. The 95% LOA of VKR on two examinations was 75% and 72.2%, respectively, with ICC of 0.510 and 0.577 respectively. Conclusion Time-SLIP contrast-enhanced imaging is highly reproducible for the display of the normal renal arteries and their branches. It is of great significance in renal artery disease, screening before kidney transplantation, assessment of efficacy after renal transplantation, and follow-up .