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患者男性,36岁。面部无明显诱因出现多个米粒大的结节2个月,逐渐增多,无破溃,偶有痒感。皮肤科检查:面部见多个红色丘疹、斑疹,直径1～5 mm,表面光滑,孤立存在、无融合,眼周较为集中。病理检查巨检:梭形皮肤组织0.8 cm×0.4 cm×0.3cm大小,皮面中心稍隆起,表面完整,无破溃,色泽正常。镜检:表皮完整,无破溃(图1),真皮浅层至皮下组织中见较多上皮样细胞团,结节状分布,可见个别多核巨细胞和少量干酪样坏死(图2,3),上皮样细胞团周围有较多淋巴细胞浸润。病变破坏汗腺、毛囊(图4)。
Male patient, 36 years old. No significant incentive to face a number of large grains of rice nodules 2 months, gradually increased, no ulceration, occasional itching. Dermatology examination: see the face of multiple red papules, rash, diameter 1 ~ 5 mm, the surface is smooth, isolated exist, no fusion, the eye is more concentrated. Pathological examination of macroscopic examination: fusiform skin tissue 0.8 cm × 0.4 cm × 0.3cm size, leather center slightly uplift, the surface integrity, no rupture, normal color. Microscopic examination: complete epidermis, no ulceration (Figure 1), superficial dermis to subcutaneous tissue see more epithelial cell mass, nodular distribution, showing a few multinucleated giant cells and a small amount of caseous necrosis (Figure 2,3) , Epithelial cell mass around more lymphocytes infiltration. Lesions sweat sweat glands, hair follicles (Figure 4).