论文部分内容阅读
目的 :观察全身炎症反应综合征 (SIRS)患者空腹血糖 (FBG)、胰岛素 (FINS)和肿瘤坏死因子 α(TNF α)的变化。方法 :符合SIRS诊断 32例禁食 12h ,于次晨空腹抽取肘静脉血 5ml,测定FBG、FINS和TNF α ,并测算胰岛素敏感指数 (ISI)。结果 :SIRS组和对照组相比FBG差异无显著性 (P >0 .0 5 ) ,FINS、TNF α显著高于对照组 (P <0 .0 1) ,而ISI显著低于对照组 (P <0 .0 1) ,说明SIRS患者存在胰岛素抵抗 (IR)。器官功能不全的患者IR更为严重 ,FINS、TNF α显著高于器官功能正常组 (P <0 .0 1) ,ISI显著低于器官功能正常组 (P <0 .0 5 )。结论 :IR与SIRS的发生、发展和预后有关
Objective: To observe the changes of fasting blood glucose (FBG), insulin (FINS) and tumor necrosis factor α (TNF α) in patients with systemic inflammatory response syndrome (SIRS). Methods: According to the 32 cases diagnosed by SIRS fasting for 12 hours, 5ml elbow venous blood was drawn on the next morning. The FBG, FINS and TNFα were measured and the insulin sensitivity index (ISI) was measured. Results: There was no significant difference in FBG between SIRS group and control group (P> 0.05), while FINS and TNFα were significantly higher than those in control group (P <0.01), but ISI was significantly lower than that in control group <0 .01), indicating insulin resistance (IR) in SIRS patients. Patients with organ dysfunction were more severe in IR, FINS, TNFα were significantly higher than normal organ function group (P <0.01), ISI was significantly lower than normal organ function group (P <0.05). Conclusion: IR is related to the occurrence, development and prognosis of SIRS