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为了解UU感染流产患者血清中肿瘤坏死因子αTNFα)和白细胞介素 6IL 6的变化 ,用EL1SA法定量检测 2 8例宫内感染和 18例先兆流产患者血清。结果发现在宫内感染期和抗生素治疗前TNFα 和LL 6血清水平明显高于正常同孕期孕妇 (P <0 .0 0 1)。治疗后 ,UU转阴 ,TNFα 和IL 6血清水平下降接近正常孕妇 ,患者保胎成功 ,结论 :在确诊为UU感染性流产患者中 ,TNFα 和IL 6血清水平的变化在预示UU宫内感染的发生和治疗效果评定方面有一定临床意义
In order to understand the changes of serum tumor necrosis factor alpha (TNF) TNFα and interleukin 6 IL 6 in patients with UU infection and abortion, the serum levels of 28 intrauterine infection and 18 cases of threatened abortion were detected quantitatively by EL1SA. The results showed that serum levels of TNFα and LL 6 before intrauterine infection and antibiotic treatment were significantly higher than those of normal pregnant women (P <0.01). After treatment, the UU was negative and TNFα and IL-6 serum levels dropped close to those of normal pregnant women, and the patient was successfully miscarried. CONCLUSIONS: Serum levels of TNFα and IL-6 in patients diagnosed with UU-infective abortion are significantly different in serum levels predictive of UU intrauterine infection Occurrence and evaluation of the therapeutic effect of a certain clinical significance