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乳腺癌是妊娠期妇女最常见的恶性肿瘤之一,第1例妊娠期乳腺癌的报道可追溯到1869年。妊娠相关乳腺癌(pregnancy-associated breast cancer,PABC)是指妊娠期或分娩后1年内诊断的原发性乳腺癌,发病率为3/10 000~1/3 000,占乳腺恶性肿瘤的0.2%~3.8%,在45岁以下的育龄妇女中,患病率达7%~14%~([1])。随着乳腺癌发病率的增加和女性生育期的推迟,PABC的发病率呈增高趋势。瑞典卫生注册处统
Breast cancer is one of the most common malignant tumors in pregnant women, the first case of gestational breast cancer can be traced back to 1869. Pregnancy-associated breast cancer (PABC) refers to the primary breast cancer diagnosed within 1 year after pregnancy or childbirth, with a prevalence of 3/10 000 to 1 000 000, accounting for 0.2% of breast malignancies ~ 3.8%. Among the women of childbearing age under 45, the prevalence rate is 7% ~ 14% ~ ([1]). With the increase of breast cancer incidence and the delay of female reproductive period, the incidence of PABC is increasing. Swedish Health Registry