论文部分内容阅读
参与吞噬反应的细胞和体液因子吞噬细胞一、中性粒细胞:由骨髓的干细胞所制造,成人每天约需制造126×10~9个中性粒细胞。成熟的中性粒细胞不断由骨髓中释出至周围血液。它在周围血中的寿命约6～7小时,如进入组织,则不能再返回血液,它在组织内的半寿期约4～5天。中性粒细胞受到趋化物质的刺激后,能迅速和准确地进入炎症区域,特别在调理素的作用下进行活跃的吞噬和发挥其杀菌效能。未成熟的中性粒细胞含有许多线粒体,成熟后这些线粒体逐渐缩小并含大量糖原。中性粒细胞依靠糖原分解而获得能量,特别是可通过持续的无氧酵解而供能,这使中性粒细胞能在缺氧的组织和渗出液中发挥作用。中性粒细胞含有二种颗粒:①原始颗粒:在细胞的早期阶段形成,含溶菌酶和大量髓过氧化物酶;②继生颗粒:在成熟细胞中为多,含乳铁蛋白和
Phagocytosis of cells and humoral factors involved in phagocytosis First, neutrophils: made from bone marrow stem cells, about 126 × 10 ~ 9 neutrophils need to be made per day for adults. Mature neutrophils are constantly released from the bone marrow to the surrounding blood. Its life in the surrounding blood about 6 to 7 hours, such as entering the organization, you can not return to the blood, its half-life in the organization of about 4 to 5 days. When neutrophils are stimulated by chemotactic substances, they can rapidly and accurately enter the inflammatory area, actively phagocytosis and exert their bactericidal effect under the action of the opsonin. Immature neutrophils contain many mitochondria, mature mitochondria gradually shrink and contain a large number of glycogen. Neutrophils rely on the breakdown of glycogen to gain energy, especially through sustained anaerobic glycolysis, which allows neutrophils to function in hypoxic tissues and exudates. Neutrophils contain two kinds of particles: ① primordial particles: formed in the early stages of cells, containing lysozyme and a large number of myeloperoxidase; ② following particles: in mature cells, containing lactoferrin and