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自从Whitfild提出空气层流原理以后,层流系统首先用于工业生产过程中防止尘埃粒子的污染,以后推广应用于微生物学、医学和药学研究。七十年代前后,层流柜和层流架开始作为SPF动物和无菌动物生产及研究的工具,随之出现了大型层流系统,用于生产高质量的实验动物。层流架内饲养动物,不但能防止架外微生物的污染,在适当的笼间距下,还可免除架内笼间的交叉污染,在某些研究中可弥补隔离器的不足。1983年国内首次试制成功了生物洁净层流架。为了评价国产层流架的实用价值,以便进一步改进和推广,于1984年5～12月进行了使用研究。材料和方法 1.SSJ-CJ-Ⅰ型超净生物层流架为佘山净化设备厂产品。安置于基本封闭的小房间内。室内自然光照,人工控制温度25℃左右,机械通风。采用半透明
Since Whitfild proposed the air laminar flow principle, the laminar flow system was first used to prevent the pollution of dust particles in the industrial production process and was subsequently applied in microbiology, medicine and pharmacy research. Since the 1970s, as a tool for the production and research of SPF animal and aseptic animals, laminar flow shelves and laminar flow shelves began to emerge as large-scale laminar flow systems for the production of high-quality laboratory animals. Laminar shelves feeding animals, not only can prevent the microbial contamination outside shelves, at the appropriate cage spacing, but also to eliminate the cross-cage cross-contamination, in some studies can make up for the lack of isolators. In 1983 the first successful trial of biological clean laminar flow shelf. In order to evaluate the practical value of the domestic LHD, in order to further improve and promote the use of the study conducted from May to December 1984. Materials and methods 1.SSJ-CJ-Ⅰ type of ultra-clean biological laminar flow frame for the Sheshan purification plant products. Placed in the basic closed small room. Indoor natural light, artificial temperature control at about 25 ℃, mechanical ventilation. Translucent