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[目的]观察胃舒胶囊联合奥美拉唑治疗消化性溃疡(PU)的疗效。[方法]将140例患者随机分为2组,2组均先给予标准三联疗法,连服1周,根除幽门螺杆菌(Hp)。之后对照组给予奥美拉唑20 mg,每日1次;治疗组在对照组治疗的基础上联合胃舒胶囊3粒,每日3次口服。2组均治疗4周后复查胃镜,判断疗效。[结果]治疗组临床治愈48例(68.6%),总有效率为92.9%;对照组临床治愈29例(41.4%),总有效率为81.4%。治疗组临床治愈率、总有效率均显著高于对照组(P<0.05)。[结论]胃舒胶囊联合奥美拉唑治疗PU的疗效满意,显著优于单用奥美拉唑,值得临床推广。
[Objective] To observe the curative effect of Weishu capsule combined with omeprazole on peptic ulcer (PU). [Methods] One hundred and forty patients were randomly divided into two groups. The two groups were given standard triple therapy first, even for 1 week to eradicate Helicobacter pylori (Hp). After that, the control group was given omeprazole 20 mg once daily. The treatment group was given 3 capsules of Weishu capsule and 3 times daily on the basis of the control group. 2 groups were treated 4 weeks after the review gastroscopy to determine the efficacy. [Results] In the treatment group, 48 cases (68.6%) were cured and the total effective rate was 92.9%. The control group was cured in 29 cases (41.4%) and the total effective rate was 81.4%. The clinical cure rate and total effective rate in the treatment group were significantly higher than those in the control group (P <0.05). [Conclusion] Weisu capsule combined with omeprazole in the treatment of PU is satisfactory, which is significantly better than omeprazole alone, which is worthy of clinical promotion.