Construction and Expression of DNA Vaccine pIRES-Sj97-Sj14-Sj26 and Its Immunogenicity in Mice

• 作 者: 刘朔婕 程继忠 唐成武 马彦彬 王淑玉 郭萍 段秋红 高红
• 机 构: DepartmentofBiochemistryandMolecularBiology
• 出 处: 华中科技大学学报：医学英德文版
• 发表日期: 2007年6期
• 关键词: 血吸虫病 DNA疫苗免疫法 预防策略 基因表达 基因结构 schistosoma japonicum Sj 14 Sj26 Sj97 DNA vaccine i
• 基金项目: This project was supported by grants from National Natural Sciences Foundation of China （No. 30471603）.

To find a new preventive strategy for the infection of Schistosoma japonica, plasmid pIRES-Sj97-Sj14-Sj26 that contains fatty binding protein (Sj14), GST (Sj26) and paramyocin (Sj97) that are expressed on the membrane, was constructed. RT-PCR was used to