Down-modulation of heat shock protein 70 and up-modulation of Caspase-3 during schisandrin B-induced

• 作 者: Yi-FengWu Ming-FuCao Yan-PingG
• 机 构: CollegeofLifeSciences,CollegeofLifeSciences,SchoolofMedicine
• 出 处: 世界胃肠病学杂志：英文版（电子版）
• 发表日期: 2004年20期
• 关键词: 向下调节 热休克 蛋白质70 下调节 CASPASE-3 五味子 细胞调亡 B-感应 SMMC-7721 肝细胞癌 癌细胞
• 基金项目: Supported by the National Key Technologies Research and Development Program of China during the 10th Five-Year Plan Period,No.2002BA760C

AIM: To investigate the effect of schisandrin B (Sch B) on proliferation and apoptosis of human hepatoma SMMC-7721 cells in vitro and regulation of Hsp70 and Caspases-3, 7, 9 expression by Sch B. METHODS: Human hepatoma cell line SMMC-7721 was cultured an