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目的 分析卵巢外腹膜浆液性乳头状癌 (extraovarianperitonealserouspapillarycarcinoma ,EPSPC)的临床特点、诊治及预后。方法 选自 1995年 1月至 1998年 12月在我院收治的 9例EPSPC病人 ,对其病例资料进行回顾性分析。结果 所有病人均行肿瘤细胞减灭术 ,术中腹腔放 5 -FU 1 0g ,术后行CAP化疗 6～ 8个疗程。9例中 2例正在化疗 ,2例复发且正在化疗 ,5例死亡。平均存活期 2 1 1个月。结论 EPSPC为女性腹膜原发恶性肿瘤 ,与卵巢乳头状浆液性腺癌 (papillaryserousovarincarcinoma ,PSOC)同源 ,其预后与手术的彻底性、及时足量化疗相关。CA12 5可作为诊断及监测预后的指标之一。
Objective To analyze the clinical characteristics, diagnosis, treatment and prognosis of extraovarian peritoneal septal pseudopapillary carcinoma (EPSPC). Methods Nine patients with EPSPC admitted to our hospital from January 1995 to December 1998 were retrospectively analyzed. Results All patients underwent cytoreductive surgery. The patients received 5 -FU 10 g intraperitoneally and 6 to 8 courses of CAP chemotherapy. Of the 9 cases, 2 were on chemotherapy, 2 were recurrent and were undergoing chemotherapy, and 5 died. The average survival period is 211 months. Conclusions EPSPC is a primary malignant tumor of female peritoneum and is homologous to papillary serousovarincarcinoma (PSOC). Its prognosis is related to the thoroughness of surgery and timely and adequate chemotherapy. CA12 5 can be used as one of the indicators for diagnosis and monitoring of prognosis.