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目的分析鼻塞式无创同步间歇指令通气(n SIMV)治疗新生儿呼吸衰竭的临床疗效。方法 66例呼吸衰竭新生儿,采用随机数字表法分为观察组和对照组,各33例。在常规治疗的基础上,观察组行n SIMV治疗,对照组行鼻塞式持续气道正压通气(n CPAP)治疗。比较两组治疗效果。结果治疗6 h,观察组患儿动脉血氧分压(Pa O2)高于对照组,动脉二氧化碳分压(Pa CO2)、吸氧分数(Fi O2)明显低于对照组(P<0.05);观察组呼吸支持时间、气管插管上机率、CO2潴留率、低氧血症率优于对照组(P<0.05)。结论 n SIMV能有效改善新生儿呼吸衰竭患者血气分析指标,缩短呼吸支持时间,提高治疗效果。
Objective To analyze the clinical efficacy of nasal plug noninvasive synchronized intermittent mandatory ventilation (n SIMV) in the treatment of neonatal respiratory failure. Methods Sixty-six neonates with respiratory failure were divided into observation group and control group by random number table method, with 33 cases in each group. On the basis of routine treatment, the observation group received n SIMV treatment and the control group received nasal continuous positive airway pressure (n CPAP) treatment. Compare the treatment effect of two groups. Results After 6 hours of treatment, the PaO2 in the observation group was higher than that in the control group. The PaCO2 and FiO2 in the observation group were significantly lower than those in the control group (P <0.05). The observation group respiratory support time, endotracheal intubation rate, CO2 retention, hypoxemia than the control group (P <0.05). Conclusion n SIMV can effectively improve neonatal respiratory failure patients blood gas analysis indicators, shorten the respiratory support time and improve the therapeutic effect.