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目的分析并探讨母亲乙型肝炎病毒感染与子代性别的关系。方法对哈尔滨市南岗区和道外区2000年1月~2005年12月所有有接生能力医院的产妇病案进行回顾性调查。调查内容包括:产妇基本情况,分娩时情况,新生儿情况。结果共调查18 935名母亲。其中HBsAg正常组18 085例,共娩出9 532名男婴和8 553名女婴,出生性别比为111.45。HBsAg携带组850例,娩出437名男婴和413名女婴,子代性别比为105.81。HBsAg携带组与正常组子代性别差异无统计学意义(χ2=0.546,P=0.46)。结论母亲HBsAg感染对子代性别无影响。
Objective To analyze and explore the relationship between maternal hepatitis B virus infection and sex of offspring. Methods Retrospective investigation was carried out on maternal medical records of all clinics with admission abilities from January 2000 to December 2005 in Nangang district and Daowai district of Harbin. The survey includes: maternal basic situation, childbirth situation, the situation of newborns. Results A total of 18,935 mothers were surveyed. Among 18 085 cases with normal HBsAg group, 9,532 boys and 8,553 girls were delivered with a sex ratio at birth of 111.45. Among 850 HBsAg-bearing patients, 437 boys and 413 girls were delivered with a sex ratio of 105.81. The sex difference between HBsAg-carrying group and normal group was not statistically significant (χ2 = 0.546, P = 0.46). Conclusion Maternal HBsAg infection has no effect on offspring sex.