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羟脯氨酸(hydroxyproline)简称Hp是一种非必须氨基酸,是机体内结缔组织中胶原纤维的主要成份之一。胶原纤维广泛分布于全身各器官中,所以胶原蛋白是机体内含量最多的蛋白质,约占人体蛋白质总量的三分之一。利用羟脯氨酸在胶原蛋白中含量最高这一特点,通过对尿液中羟脯氨酸排出量的测定,成为衡量人体或其他有机体胶原组织代谢的重要指标。儿童尿Hp的排出情况,虽然国内外均有报导,但其排出量与儿童少年青春期发育、性别间的差异等方面的关系、目前报导尚少。为进一步探讨以上情况,以便今后利用这一生化指标更客观的反映儿童少年的生长发育状况提供科学依据、我们对济南市7～17岁儿童少年24小时尿Hp排出量进行了测定、对有关的形
Hydroxyproline, abbreviated as Hp, is an essential amino acid that is one of the main components of collagen fibers in the body’s connective tissue. Collagen fibers are widely distributed in various organs of the body, so collagen is the most abundant protein in the body, accounting for about one-third of the total human protein. The use of hydroxyproline in the highest content of collagen in this feature, through the determination of hydroxyproline in urine, as a measure of human or other organisms, an important indicator of collagen metabolism. The urinary Hp excretion in children has been reported both at home and abroad. However, the relationship between the amount of urinary Hp excretion and the adolescent development of adolescents and the gender differences is still low. In order to further explore the above situation so as to provide a scientific basis for using this biochemical index to objectively reflect the growth and development status of children and adolescents in the future, we measured the 24-hour urinary Hp excretion of juvenile children aged 7 to 17 years in Jinan City. shape