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慢性化脓性中耳炎的病原菌,以绿脓杆菌、金黄色葡萄球菌(以下简称金葡菌)及变形杆菌为主,常常因为产生耐药性而带来治疗上的困难,抗菌素类滴耳剂单独应用已较普遍,与磺胺类药物联合应用较少。我们将硫酸盐链霉素与磺胺噻唑联合配成滴耳剂,做抑菌效果测定及临床疗效观察,兹将部分结果报告于后。材料来源及实验方法在下农村(北京大兴县)巡回医疗中,对64例慢性化脓性中耳炎患者70只耳做了脓培养,获绿脓杆菌10株,占14.3％;金葡菌11株,占15.7％;变形杆菌23株,占32.9％。在北京同仁医院门诊对282例慢性化脓性中耳炎患者292只耳做了脓培养,获绿脓杆菌109株,占37.3％;金葡菌79株,占27.3％;变形杆菌19株,占6.5％。保留部分菌种以做药物敏感试验。
Chronic suppurative otitis media pathogens to Pseudomonas aeruginosa, Staphylococcus aureus (hereinafter referred to as Staphylococcus aureus) and Proteus-based, often because of the resulting drug resistance and bring about the treatment of difficulties, antibiotic ear drops alone Has been more common, and sulfa drugs combined with less. We will sulfate sulfathiazole sulfamethoxazole together dubbing agent, antibacterial effect determination and clinical observation, we will report some of the results later. MATERIALS AND EXPERIMENTAL METHODS In the pediatric medical treatment of 64 rural patients with chronic suppurative otitis media, 10 strains of Pseudomonas aeruginosa, accounting for 14.3%, were included in the tour of medical treatment in rural areas (Daxing County, Beijing). 11 strains of Staphylococcus aureus 15.7%; 23 strains of Proteus, accounting for 32.9%. In Beijing Tongren Hospital outpatient 282 cases of chronic suppurative otitis media in 292 ears made pus culture, 109 strains of Pseudomonas aeruginosa, accounting for 37.3%; Staphylococcus aureus 79 strains, accounting for 27.3%; 19 strains of Proteus, accounting for 6.5% . Keep some bacteria for drug sensitivity test.