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从SLE患者的临床上正常皮肤切片,用直接荧光抗体方法检查,常可在真皮——表皮的接合处见到免疫球蛋白和补体“带”的沉积,此种方法称之为“免疫荧光带试验”。在其它风湿性综合征中的正常皮肤很少发现为阳性,因此阳性试验在确诊SLE时是有价值的。复合结缔组织疾病临床上具有类似SLE、硬皮病、多发性肌炎的指征,一般认为它和SLE相比有更好的预后,但有时不易和SLE相鉴别。本文目的是企图通过免疫荧光带试验来鉴别这二种疾病。
Clinically normal skin sections from patients with SLE are examined by direct fluorescent antibody methods and the deposition of immunoglobulins and complement “bands” can often be seen at the dermis-epidermal junction, a technique known as “immunofluorescence banding test”. Normal skin in other rheumatic syndrome is seldom found to be positive, so a positive test is valuable in diagnosing SLE. Composite connective tissue disease clinically similar to SLE, scleroderma, polymyositis indications generally believed that it has a better prognosis than SLE, but sometimes not easy and SLE differential. The purpose of this article is to attempt to identify both of these diseases by immunofluorescence band tests.