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作者报告用氮芥治疗慢性腎炎腎病期患者23例,其中男20例,女3例。年龄在20～59岁之間,而21～40岁者19例。全部病例均系住院且經时間不等的其它治疗无效者。使用氮芥治疗时,除采用无盐或低盐飲食及抗菌素預防或控制感染外,停止使用一切有关腎炎和利尿消肿的药物。氮芥每隔日注射一次,7～10次为一疗程。初剂量为3毫克,第2次为4毫克,第3次及以后为5毫克,总量約32～47毫克。注射氮芥前,先以5%
The authors report the use of nitrogen mustard treatment of chronic nephritis in patients with 23 cases, of which 20 males and 3 females. The age of 20 to 59 years old, and 21 to 40 years old in 19 cases. All cases were hospitalized and the treatment of ineffective other time. Use nitrogen mustard treatment, in addition to the use of salt-free or low-salt diet and antibiotics to prevent or control infection, to stop using all the nephritis and diuretic swelling of drugs. Nitrogen mustard injection every other day, 7 to 10 times for a course of treatment. The initial dose of 3 mg, the second 4 mg, the third and subsequent 5 mg, a total of about 32 to 47 mg. Before nitrogen mustard injection, first with 5%