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光镜及电镜检查证明,人肺癌细胞在器官培养中其侵袭力较强,在第2天即可侵入器官,侵入过程可分为5个阶段:既靠拢,粘着,紧贴,伸出伪足沿细胞间隙侵入,并在器官内形成癌细胞巢。对癌细胞侵入过程微细变化的三种表现形式,进行较详细的描述和讨论。我们曾利用人类不同癌细胞株如鼻咽癌细胞株(CNE)及肝癌细胞株(BEL-7402)等检查了体外培养条件下癌细胞侵袭特性,已发现一些有意义的现象和特征。为找出不同癌细胞株侵袭特性的共同规律,我们应用人肺癌细胞株在器官培养条件下,观察癌细胞侵袭的细微过程。
Light microscopy and electron microscopy proved that human lung cancer cells in the organ culture of its strong invasive in the first 2 days to invade the organ, the invasion process can be divided into five stages: both close together, stick, close, extending the pseudopodia Invade along the intercellular space and form nests of cancer cells within the organ. The cancer cells in the process of subtle changes in the three forms of expression, a more detailed description and discussion. We have used human cancer cell lines such as nasopharyngeal carcinoma cell line (CNE) and hepatocellular carcinoma cell line (BEL-7402) to examine the in vitro culture conditions of cancer cell invasion characteristics, we have found some meaningful phenomena and characteristics. To find out the common law of invasion characteristics of different cancer cell lines, we observed the subtle process of cancer cell invasion in human lung cancer cell line under organ culture conditions.