Using Matrix-assisted laser desorption/ionization time-of-flight mass spectrometry to analyze differ

• 作 者: Xiangyu Liao Jiayu Wan Wensen
• 机 构: DepartmentofImmunology,TheFirstClinicalMedicalCollegeofThreeGorgesUniversity,InstituteofMilitaryVete
• 出 处: 中国神经再生研究：英文版
• 发表日期: 2011年23期
• 关键词: 基质辅助激光解吸 质谱分析 飞行时间 小鼠模型 多肽 差异表达 感染 应变 prion diseases misfolded prion protein ima
• 基金项目: Supported by： the National Natural Science Foundation of China, No. 30972197 and 31072148： Science and Technology Plan Program of Jilin Province. No. 201105038

Differentially expressed polypeptides in the brain of a BALB/c mouse model infected with scrapie strain 22L were analyzed by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry.The results showed that 21 peptides were down-regulat