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对非甲非乙型肝炎的病原学还研究得很不充分,但从现有材料来看,可以肯定病原体是病毒,起码有2种以上血清型,它们之间不存在交叉免疫。下面把主要研究成果作一介绍。动物实验感染研究猩猩从世界上人工感染150只猩猩的结果表明,猩猩对非甲非乙型肝炎病毒(HNANBV)的易感性为70%。经静脉、肌肉、皮下或肝内注射有感染性血清的传染性滴度在10~6U/ml以上,但病情轻重与感染剂量无关。在猩猩中也观察到短(2～6周)、长(10～20周)2种潜伏期。在猩猩中的潜伏期与提供感染性血清
The etiology of non-A, non-B hepatitis is also poorly studied. However, from the available materials, it can be affirmed that the pathogen is a virus with at least two serotypes and no cross immunization exists between them. The following main research results for an introduction. Animal Experimental Infection Study Orangutan The results of artificial ingestion of 150 chimpanzees from around the world indicate that the susceptibility of apes to non-A, non-B hepatitis virus (HNANBV) is 70%. Infectious sera that had been injected intravenously, intramuscularly, subcutaneously or intrahepaticly had an infectious titer of 10 to 6 U / ml or more, but the severity of the disease was not related to the dose of infection. Orangutan also observed short (2 to 6 weeks), long (10 to 20 weeks) 2 kinds of incubation period. Latency in orangutans with infectious sera