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药源性味觉障碍是指药物所致味觉丧失、味觉异常和味觉减退。目前有上百种药物可引起味觉障碍。抗感染药物、心血管药物、神经精神疾病用药、抗肿瘤药物是最常见的致味觉障碍药物。体内锌离子浓度降低可能是药源性味觉障碍的主要机制之一。药源性味觉障碍能影响患者的食欲、营养摄入、生活质量与情绪状况,尤其是用药依从性。因此,医师应关注临床发生的药源性味觉障碍。
Drug-induced taste disorders refers to drug-induced loss of taste, abnormal taste and taste diminished. There are hundreds of drugs that can cause dystonia. Anti-infective drugs, cardiovascular drugs, neuropsychiatric drugs, anti-cancer drugs is the most common cause of taste disorders. Reduction of zinc ion concentration in vivo may be one of the main mechanisms of drug-induced taste disorders. Drug-induced taste disorders can affect the patient’s appetite, nutritional intake, quality of life and emotional conditions, especially medication compliance. Therefore, physicians should pay attention to the clinical drug-induced dysgeusia.