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目的探讨前置胎盘剖宫产术前应用米索前列醇减少术中术后出血的临床效果。方法将妊娠晚期124例前置胎盘患者随机分为2组:研究组62例、对照组62例,2组均按常规行剖宫产术,研究组术前予米索前列醇0.4mg直肠置药。比较2组术时、术后2h及术后24h内平均累计出血量和输血率。结果研究组术时、术后2h、术后24h累计出血量均显著小于对照组(P<0.05),输血率亦低于对照组(P<0.05)。结论术前直肠置入米索前列醇能促进子宫收缩,预防前置胎盘剖宫产术时、术后出血。
Objective To investigate the clinical effect of misoprostol on preoperative placenta previa to reduce intraoperative and postoperative bleeding. Methods 124 cases of placenta previa in late pregnancy were randomly divided into two groups: study group 62 cases, control group 62 cases, two groups were routine cesarean section, the study group preoperative misoprostol 0.4mg rectal medicine. The mean cumulative blood loss and blood transfusion rate were compared between the two groups during operation, 2 hours after operation and 24 hours after operation. Results The total amount of bleeding at 2 hours and 24 hours after operation in study group was significantly lower than that in control group (P <0.05), and the transfusion rate was also lower than that in control group (P <0.05). Conclusion Preoperative placement of misoprostol in the rectum can promote uterine contractions and prevent bleeding during cesarean section.