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目的探讨子疒间前期并发心衰发生的诱因、治疗要点及预防措施。方法上海第二医科大学附属仁济医院产科心脏病监护中心,于1993年5月至2005年5月间共诊治重度子疒间前期患者105例,其中38例并发心衰(A组),67例未发生心衰(B组),对两组患者的临床资料进行回顾性分析。结果重度子疒间前期并发心衰的发生率为36.19%。A组有5例患者(15.64%)、B组有48例患者(71.64%)接受过常规产前检查,两组比较差异有显著性意义(P<0.01);A组患者的收缩压、舒张压和心率均显著高于B组,平均终止妊娠孕周则显著低于B组;左心室后负荷急剧增加是重度子疒间前期心衰发生的主要原因。心脏前负荷短期快速增加、贫血和肺部感染是诱发心衰的常见因素。结论做好常规产前检查,迅速控制重度子疒间前期患者的血压是防治心衰的关键;硫酸镁可安全有效地治疗子疒间前期心衰,但应掌握使用的时机和方法。
Objective To explore the causes, treatment points and preventive measures of premature encephalitis in children. Methods A total of 105 patients with severe preeclampsia were diagnosed and treated in Renji Hospital Obstetrics and Gynecology Center affiliated to Shanghai Second Medical University from May 1993 to May 2005. 38 patients were complicated with heart failure (group A), 67 Cases without heart failure (B group), the clinical data of two groups were retrospectively analyzed. Results The incidence of severe preeclampsia was 36.19%. There were 5 patients (15.64%) in group A, 48 patients (71.64%) in group B received conventional prenatal examination, the difference was significant between the two groups (P <0.01) Pressure and heart rate were significantly higher than the B group, the average gestational age at termination of pregnancy was significantly lower than the B group; rapid increase of left ventricular afterload is the main reason for severe premenstrual heart failure. Short-term rapid increase in preload of the heart, anemia and pulmonary infection are common causes of heart failure. Conclusions It is the key to prevention and treatment of heart failure that routine prenatal examination and rapid control of blood pressure in patients with severe preeclampsia can be safely and effectively treated with magnesium sulfate. However, the timing and methods should be used.