论文部分内容阅读
治疗呼吸系疾病经常大量长期使用肾上腺皮质类固醇,但众所周知该药大量应用可引起肌病。然而很少有人注意到长期应用对呼吸肌的影响。有些研究其对象是呼吸系疾病患者,因而无法区分是药物作用还是疾病本身的影响。为此对非呼吸系疾病患者进行了研究。 共8例肺与吸气功能正常的患者,其中急进型肾小球肾炎2例,微小病变型肾小球肾炎2例,特发性血小板减少性紫癜2例,亚急性甲状腺炎2例。用药为强地松每日 1～1.5mg/kg,用药8周后减量,并于 6周内停用。观察用药前后的吸气肌力即最大吸气压(Pmax)
Treatment of respiratory diseases often long-term use of adrenal corticosteroids, but it is well known that the large number of applications of the drug can cause myopathy. However, few have noticed the effects of long-term application on the respiratory muscles. Some studies are aimed at patients with respiratory diseases and therefore can not distinguish between the effects of drugs or the effects of the disease itself. For this non-respiratory disease patients were studied. A total of 8 cases of lung and inspiratory function in patients with normal, including 2 cases of acute glomerulonephritis, minimally invasive glomerulonephritis in 2 cases, idiopathic thrombocytopenic purpura in 2 cases, 2 cases of subacute thyroiditis. Medication for prednisone day 1 ~ 1.5mg / kg, 8 weeks after the dose reduction, and disable it within 6 weeks. Before and after treatment of inspiratory muscle strength that is the maximum inspiratory pressure (Pmax)