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目的 探讨乳头状肾细胞癌的临床病理特征及诊断标准。方法 收集 5例该肿瘤 ,作常规HE及免疫组织化学染色并与 70例非乳头状肾细胞癌比较。结果 乳头状肾细胞癌是一种特殊类型的肾细胞癌 ,临床经过长 ,生长缓慢 ,肾动脉造影表现为少血管或无血管性 ,预后较好。巨检肿瘤边界清楚 ,有出血囊性变。镜检肿瘤组织呈乳头状或管状乳头状排列 ,乳头轴心及间质内有泡沫状巨噬细胞浸润 ,有明显出血坏死。结论 乳头状肾细胞癌在临床 ,血管造影 ,病理形态 ,生物学行为上均与其他类型的肾细胞癌不同 ,应将其作为一种独立的组织学类型诊断。
Objective To investigate the clinicopathological features and diagnostic criteria of papillary renal cell carcinoma. Methods Five cases of this tumor were collected for routine HE and immunohistochemical staining and compared with 70 cases of non-papillary renal cell carcinoma. Results papillary renal cell carcinoma is a special type of renal cell carcinoma, the clinical after long, slow growth, renal artery angiography showed less or no vascular, the prognosis is good. Giant tumor border clear, hemorrhagic cystic degeneration. Microscopic examination of tumor tissue was papillary or tubular papillary arrangement of papillary axis and interstitial foam-like macrophage infiltration, with significant hemorrhage and necrosis. Conclusion Papillary renal cell carcinoma is different from other types of renal cell carcinoma in clinical, angiographic, pathological and biological behavior and should be diagnosed as an independent histological type.