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目的探讨PICU患儿发生医院内感染的临床特征,为预防和控制PICU医院内感染提供依据。方法回顾性分析89例PICU医院内感染患儿的临床资料。结果本组中呼吸系统感染63例(70.8%),泌尿系统感染13例(14.6%),消化系统感染11例(12.4%),皮肤软组织感染2例(2.2%);危重症评分≤70分、广谱抗生素应用>5d、糖皮质激素应用>5d、PICU住院天数>10d、中心静脉置管及气管插管为发生医院内感染的危险因素;89例患儿临床采集标本共分离致病菌127株,其中革兰阴性菌102株(80.3%),革兰阳性菌11株(8.7%),真菌14株(11.0%)。结论 PICU患儿具有引起医院内感染的多种高危因素,合理使用抗生素、减少ICU住院时间及减少介入性操作将有助于预防或降低PICU患儿医院内感染发生率。
Objective To investigate the clinical characteristics of nosocomial infections in children with PICU and provide evidence for prevention and control of nosocomial infections in PICU. Methods A retrospective analysis of 89 cases of PICU hospital infection in children with clinical data. Results In this group, 63 cases (70.8%) had respiratory system infection, 13 cases (14.6%) had urinary tract infection, 11 cases (12.4%) had digestive system infection and 2 cases (2.2%) had skin and soft tissue infections. , Broad-spectrum antibiotics application> 5d, glucocorticoid application> 5d, PICU hospitalization days> 10d, central venous catheterization and tracheal intubation were risk factors for nosocomial infection; 89cases of clinical samples were isolated from pathogens There were 127 strains of Gram-negative bacteria (80.3%), 11 strains of Gram-positive bacteria (8.7%) and 14 fungi (11.0%). CONCLUSIONS: PICU children have many risk factors causing nosocomial infections. Rational use of antibiotics, reduction of ICU stay and reduction of interventional interventions will help prevent or reduce the incidence of nosocomial infections in PICU children.