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目的提高肾嫌色细胞癌的诊治水平。方法复习24例肾嫌色细胞癌的临床病理资料,重新观察每例HE光镜切片,所有病例均行免疫组化检查,部分病例行胶体铁染色。结果3例行肾部分切除术,其余行根治性肾切除术,15例随访6～110个月(平均34个月),2例术后1.5～2年死于癌转移,其余无瘤存活。结论肾嫌色细胞癌是一种低度恶性、预后较好的肿瘤,病理诊断是关键,宜及早手术,提倡在术中快速病理诊断指导下决定手术方式。
Objective To improve the diagnosis and treatment of chromophobe renal cell carcinoma. Methods The clinical and pathological data of 24 patients with chromophobe renal cell carcinoma were reviewed. Every HE staining was retrospectively performed. Immunohistochemical examination was performed in all cases, and colloidal iron staining was performed in some cases. Results Three cases underwent partial nephrectomy and the other cases underwent radical nephrectomy. Fifteen patients were followed up for 6 to 110 months (average 34 months). Two patients died of cancer metastasis 1.5 to 2 years after operation, and the rest survived without tumor. Conclusion Kidney chromophobe cell carcinoma is a kind of low grade malignant tumor with good prognosis. Pathological diagnosis is the key and should be treated as early as possible. It is advocated that the operation mode should be decided under the guidance of rapid pathological diagnosis.