论文部分内容阅读
目的探讨新辅助化疗在晚期卵巢癌辅助治疗中的临床效果。方法收集我院2009年1月至2010年1月收治的晚期卵巢癌症患者40例,分为治疗组和对照组各20例,其中治疗组患者使用新辅助化疗治疗,配合常规手术治疗进行;对照组的患者使用常规手术治疗及常规化疗。在治疗结束后对两组患者的手术时间、化疗毒副反应、手术残留、术中出血等情况进行统计分析。结果治疗组患者的治疗效果与对照组患者形成鲜明对比,两组患者差异显著,P<0.05,具有统计学差异。患者一般情况改善,化疗前后评定均有明显提高。化疗毒副反应轻微。所有患者化疗后均进行了广泛性全子宫、双附件、大网膜、阑尾及受累脏器切除术和淋巴清扫术。结论在治疗晚期卵巢癌的过程中,使用新辅助化疗可以安全、快速、毒副作用较小的进行,控制患者的病症情况,有效的提高患者的手术成功率,值得在临床过程中进行推广使用。
Objective To investigate the clinical effect of neoadjuvant chemotherapy in the adjuvant treatment of advanced ovarian cancer. Methods Forty patients with advanced ovarian cancer who were admitted to our hospital from January 2009 to January 2010 were divided into treatment group and control group with 20 cases in each group. The patients in the treatment group were treated with neoadjuvant chemotherapy, Patients in the group received conventional surgery and conventional chemotherapy. At the end of the treatment, the operation time, the side effects of chemotherapy, the residue of operation and the intraoperative bleeding were analyzed statistically. Results The therapeutic effect of the treatment group was in striking contrast with that of the control group. There was significant difference between the two groups (P <0.05). The difference was statistically significant. Patients generally improved, before and after chemotherapy were significantly improved assessment. Toxicity minor chemotherapy. All patients underwent extensive hysterectomy, double attachment, omentum, appendectomy, and organ excision and lymphadenectomy after chemotherapy. Conclusion In the treatment of advanced ovarian cancer, the use of neoadjuvant chemotherapy can be safe, rapid, fewer side effects, to control the patient’s condition, and effectively improve the success rate of patients with surgery, it is worth to promote the use of the clinical process.