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目的了解湖南省孕产妇艾滋病病毒(HIV)感染状况,为开展预防艾滋病母婴传播工作提供决策依据。方法对2004年1月-2010年12月湖南省(2004-2009年8月30日为6个示范区数据,2009年9月-2010年12月为全省数据)孕产妇的HIV检测结果进行分析。结果 2004-2010年共筛查孕产妇1 223 557人,确认HIV抗体阳性者155例,总体阳性率为1.97/万。155例HIV感染孕产妇中产前确诊者98例,占63.2%;产时确诊者21例,占13.5%;产后确诊者36例,占23.3%。自愿选择终止妊娠41例,占26.5%;103例选择继续妊娠直至分娩,占66.5%,分娩的产妇中服用抗病毒药物者30例,占29.1%;其中采用三联用药者22例,占73.3%。另7例正处于孕期随访中;2人失访。103例分娩的婴儿中均为活产,其中3例出生后7 d内死亡,存活的100例婴儿中服用抗病毒药物者36例,占36.0%。结论加强孕产妇HIV检测,提高孕早期HIV检测率,加强对HIV感染孕产妇的高危管理,可以提高湖南省预防艾滋病母婴传播服务水平,降低艾滋病母婴传播率。
Objective To understand the status of HIV infection among pregnant women in Hunan Province and provide evidence for decision-making on prevention of mother-to-child transmission of AIDS. Methods The results of HIV testing of pregnant women in Hunan Province from January 2004 to December 2010 in Hunan Province (data from 6 demonstration areas on August 30, 2004 - August 2009, and data from September 2009 to December 2010 in the province) analysis. Results A total of 1 223 557 maternal pregnancies were screened from 2004 to 2010, and 155 were confirmed as HIV positive. The overall positive rate was 1.97 per 10,000. Among the 155 HIV-infected pregnant women, 98 were prenatal diagnoses, accounting for 63.2%; 21 were diagnosed during delivery, accounting for 13.5%; and 36 were diagnosed after delivery, accounting for 23.3%. Voluntary termination of pregnancy in 41 cases, accounting for 26.5%; 103 cases choose to continue pregnancy until childbirth, accounting for 66.5%, delivery of antiviral drugs in 30 cases of women, accounting for 29.1%; of which 22 cases with triple therapy accounted for 73.3% . Another 7 cases are in pregnancy follow-up; 2 were lost. Among the 103 infants who gave birth, they were all live births, of which 3 died within 7 days after birth. Of the 100 infants who survived, 36 were antiviral drugs, accounting for 36.0%. Conclusion Enhancing HIV testing of pregnant women, improving detection rate of HIV in early pregnancy, and strengthening high-risk management of pregnant women infected with HIV can improve the level of mother-to-child transmission of HIV / AIDS prevention in Hunan Province and reduce the rate of mother-to-child transmission of HIV / AIDS.