论文部分内容阅读
目的 探讨复治菌阳多耐药 (MDR)肺结核病人产生多耐药的临床原因、耐药种类及含氧氟沙星治疗方案的近期疗效。方法 利用临床资料进行总结和分析。结果 从 4 76例复治菌阳肺结核病人中发现184例有多耐药性 ,产生多耐药的主要原因是初治期间疗程不够即自行停药及间断不规则用药 ,二者共占81.5%。耐药种类多数是 3种以上 ,以异烟肼 (INH)、利福平 (RFP)和链霉素 (SM )为主。结论 抓好初治病例的系统治疗和管理是防止多耐药产生的关键。对多耐药肺结核病人可选用氧氟沙星和其它 3～ 6种敏感抗结核药联合治疗
Objective To investigate the clinical causes of multidrug resistance in multidrug resistant multidrug - resistant multidrug - resistant pulmonary tuberculosis (MDR) patients, the types of drug resistance and the short - term curative effect of ofloxacin. Methods The clinical data were summarized and analyzed. Results A total of 184 cases of multi-drug resistance were found in 476 retaliation positive pulmonary tuberculosis patients. The main cause of multi-drug resistance was the discontinuation of medication and intermittent irregular medication during initial treatment, which accounted for 81.5% . Most of the resistant species are more than 3, with INH, RFP and SM. Conclusion It is the key to prevent systemic multi-drug resistance that the systematic treatment and management of newly diagnosed cases should be done. Of multi-resistant tuberculosis patients can choose ofloxacin and other 3 to 6 kinds of sensitive anti-TB drug combination therapy