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目的通过分析2013—2015年沈阳市疑似麻疹病例血清学检测结果,为制定消除麻疹防治措施提供依据。方法收集沈阳市2013—2015年麻疹疑似病例监测资料,用Excel 2007进行数据统计分析。结果 2013—2015年沈阳市共报告疑似麻疹病例4 243例,检测合格血标本3 666例,检出麻疹IgM阳性1 629例,麻疹IgM阳性率对44.43%。出疹后4~7 d的血标本麻疹IgM阳性率最高,为53.66%。1—5月为高发期。麻疹IgM阳性率以<8月龄人群最多。有明确免疫史的疑似麻疹病例麻疹IgM抗体阳性率明显低于无免疫史的病例。结论及时有效的疫苗接种是消除麻疹的重要手段;采血时间是影响麻疹IgM结果的重要影响因素,假阴性病例排除需要慎重。
Objective To analyze the serological test results of suspected measles cases from 2013 to 2015 in Shenyang and provide the evidence for the prevention and cure of measles. Methods The surveillance data of measles suspected cases from 2013 to 2015 in Shenyang were collected and the data were analyzed with Excel 2007. Results A total of 4 243 cases of measles were detected in Shenyang City during 2013-2015. A total of 3 666 cases of measles were detected, of which 1 629 were positive for measles and 44.43% for measles. The positive rate of measles IgM in the blood samples from 4 to 7 days after rash was the highest (53.66%). 1-5 months for the high incidence period. Measles IgM positive rate of <8 months of age groups most. The positive rate of measles IgM antibody in suspected measles cases with a clear history of immunization was significantly lower than those without immunization history. Conclusions Prompt and effective vaccination is an important means to eliminate measles. Blood sampling time is an important influencing factor of measles IgM results. Exclusion of false negatives needs caution.