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目的探索2016年浙江省德清县1例人感染H7N9禽流感病例的感染来源,为防控人禽流感提供科学依据。方法调查确诊病例和密切接触者,采集外环境标本进行实验室检测。结果患者确诊为人感染H7N9禽流感病例,经救治无效死亡。患者年龄76岁,有高血压病史,发病前7天无活禽接触史,有农贸市场暴露史,虽然该农贸市场无活禽交易,但市场内杀白禽摊位处检出1份H7N9流感病毒核酸阳性的污水标本。3名杀白禽摊主的活禽关养宰杀场所均有H7N9流感病毒核酸阳性标本检出。13名密切接触者均未出现急性呼吸道感染症状。结论病例感染来源于受H7N9病毒污染的农贸市场的可能性较大,建议加强农贸市场的卫生管理和消毒工作,规范禽类宰杀与销售。
Objective To explore the source of infection of a human case of H7N9 bird flu in Deqing County, Zhejiang Province in 2016 and provide a scientific basis for the prevention and control of human bird flu. Methods Investigate confirmed cases and close contacts, collect environmental samples for laboratory testing. Results The patient was diagnosed as H7N9 bird flu and died of treatment failure. The patient was 76 years old and had a history of hypertension. There was no history of live poultry contact within 7 days before the onset of illness. There was a history of exposure to farmers’ markets. Although no live poultry was traded in this farmer’s market, 1 H7N9 influenza virus Nucleic acid-positive sewage samples. Three white-beast stalls of live birds were killed and slaughtered places have H7N9 influenza virus nucleic acid positive specimens were detected. None of the 13 close contacts experienced symptoms of acute respiratory infection. Conclusions The case-based infection is more likely to come from the farmer’s market polluted by H7N9 virus. It is suggested to strengthen the hygiene management and disinfection of farmer’s market and regulate the slaughter and sale of poultry.