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結核菌素(簡称結素)是1890年Koch氏創制的。創制的目的是企图以此治疗結核病。当时他还不了解变态反应的意义,也不知道結素有診断結核感染的用途。虽然他治疗的企图是失敗了,而結素在診断方面的用途仍被广泛采用着;在进行結核感染率的調查,开展卡介苗接种,作为临床鉴别診断等方面,結素发揮了相当的作用。至于結素試驗能否使結核病恶化,迄今为止国內文献罕見报告。我們于1956年与1959年分别遇到2例,特报告如下,以供参考,并希引起临床上应用时有所警惕。例1:男性,22岁,未婚,学員。于1956年2月22
Tuberculin (referred to as knot element) was created in 1890 Koch’s. Created to try to treat tuberculosis. At that time he did not understand the significance of allergies, do not know the end result of the diagnosis of tuberculosis infection. Although his attempt to cure was unsuccessful, the use of clues in diagnosis was still widely adopted; catabasis played an important role in investigating the prevalence of tuberculosis, in the course of BCG vaccination, as a clinical differential diagnosis, etc. . As for the tuberculin test can lead to deterioration of the domestic literature so far rarely reported. We met two cases in 1956 and 1959 respectively, the special report is as follows for reference, and hopefully arouse vigilance in clinical application. Example 1: Male, 22 years old, single, student. On February 22, 1956