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正在服用抗抑郁药的患者,饮低浓度酒精或无酒精饮料是否有禁忌? 抗抑郁药,尤其是老的三环类复合物,例如阿米替林和丙咪嗪与酒精互相作用有两种方式:其一为抗抑郁药的镇静作用与简单加入酒精相合并而起作用,其二为药物的吸收与代谢由于酒精的存在而改变。当约有30g(1～2 pint)酒精消耗时才能测出其副作用。含低浓度酒精的贮藏啤酒常含酒精0.5～1%,因此,最少需要5pint来消耗才能测出与抗抑郁药的相互作用。有些酒只含0.3%酒精,一般容量很少与抗抑郁药相互作用。一些酒及贮藏啤酒描述为无酒精,但其实含很少量约为0.05%酒精,这样少容量与药物相互作用毫无意义。在这些低浓度酒精饮料中没有加入其它物质,例如生物原性胺来与抗抑郁药相作用。大多数低浓度酒精饮料制作与高浓度酒精饮料相同,只是减少酒精量而已。因此,一般来说,在服用抗抑郁药时饮用低浓度
Are antidepressants, especially older tricyclic compounds, such as amitriptyline and imipramine, interacting with alcohol in patients taking antidepressants, drinking low-alcohol or non-alcoholic beverages? Modes: One is that the anti-depressant sedative effect is combined with simple addition of alcohol, and the other is that the absorption and metabolism of the drug are changed due to the presence of alcohol. When about 30g (1 ~ 2 pint) alcohol consumption can be measured when the side effects. Lager beer with a low concentration of alcohol often contains 0.5-1% alcohol, so a minimum of 5 pint is needed to measure the interaction with antidepressants. Some wines contain only 0.3% alcohol, and their general capacity rarely interacts with antidepressants. Some wines and lager are described as non-alcoholic, but in fact they contain very small amounts of about 0.05% alcohol, meaning that there is no point in having less capacity to interact with the drug. No other substances, such as biogenic amines, are added to these low-level alcoholic beverages to interact with antidepressants. Most low-alcohol drinks are produced in the same way as high-alcohol drinks, but just to reduce the amount of alcohol. Therefore, in general, drink low concentrations when taking antidepressants