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目的探讨十二指肠乳头旁憩室(periampullary diverticula,PAD)与胆胰疾病的关系,及其对内镜下逆行胰胆管造影(endoscopic retrograde cholangio pancreatography,ERCP)的成功率和手术相关并发症的影响.方法回顾性分析2016-01/2016-12在南昌大学第一附属医院接受ERCP术的1455例患者的病例资料,按患者是否有PAD,分为PAD组(293例)和非PAD组(1162例),分析并比较2组之间胆胰疾病的发生率、ERCP手术成功率及其术后并发症发生率.结果PAD发生率随年龄的增大而升高(P<0.001).PAD组胆系结石发生率高于非PAD组(P=0.012).PAD组化脓性胆管炎、急性胰腺炎、胰头癌发生率均高于非PAD组(P<0.05).PAD组ERCP术后出血、穿孔、术后胰腺炎、高淀粉酶血症等并发症发生率均高于非PAD组(P<0.05).2组ERCP术成功率无明显差异(P>0.05).结论PAD容易并发胆胰疾病,会增加ERCP并发症发生率,但对ERCP术成功率没有影响.
Objective To investigate the relationship between periampullary diverticula (PAD) and biliary and pancreatic diseases and its impact on the success rate of endoscopic retrograde cholangio pancreatography (ERCP) and surgical complications Methods The data of 1455 patients who underwent ERCP at the First Affiliated Hospital of Nanchang University from January 2016 to December 2016 were retrospectively analyzed. The patients were divided into PAD group (293 cases) and non-PAD group (1162 (P <0.001) .PAD group (P <0.001) .The incidence of gallstone and pancreas disease, the success rate of ERCP operation and the incidence of postoperative complications between the two groups were analyzed and compared.Results The incidence of PAD increased with age (P <0.001) The incidence of gallstone was higher than that of non-PAD group (P = 0.012) .The incidence of suppurative cholangitis, acute pancreatitis and pancreatic head cancer in PAD group was higher than that in non-PAD group (P <0.05) , Perforation, postoperative pancreatitis, high amyloidosis and other complications were higher than non-PAD group (P <0.05) .There was no significant difference in the success rate of ERCP between the two groups (P> 0.05) .Conclusion PAD is easily complicated with gall Pancreatic diseases increase the incidence of complications of ERCP but have no effect on the success rate of ERCP.