【摘 要】
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Lymphomatoid granulomatosis(LG)is an angiocentric lymphoproliferative disease.It usually involves lung,skin,and central nervous system,but splenomegaly and panc
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Lymphomatoid granulomatosis(LG)is an angiocentric lymphoproliferative disease.It usually involves lung,skin,and central nervous system,but splenomegaly and pancytopenia are the rare manifestations of the disease.We report a 15-year-old boy presented with fever,dry cough and dyspnea from two months ago,after admission patient had nodular lesions on the left leg and hepatosplenomegaly.Then he manifested neurologic signs such as seizure,aphasia and right-sided hemiplegia.Chest X-ray and CT scan revealed bilateral pulmonary nodules predominantly in lower lobes and peripheral lung fields.Laboratory exams showed pancytopenia.Skin biopsy was done,and histopathological examination and immunohistochemistry evaluation confirmed lymphomatoid granulomatosis.He was treated with steroid and cyclophosphamide but succumbed by neurologic involvement.
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