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目的：探讨剖宫产术后病人硬膜外连续注射局麻药镇痛对泌乳素及婴儿体重的影响。方法：选择６０ 例健康足月产妇，择期在硬膜外麻醉下施行剖宫产术。术毕随机等分为镇痛组和对照组。镇痛组（ ｎ ＝ ３０） 行硬膜外镇痛， 注入０ ．２ ％ 布比卡因（２ ｍｌ／ｈ） 持续７２ｈ 镇痛。对照组（ｎ ＝ ３０ ） 术毕拔出硬膜外导管。两组采用放射免疫分析法测定血浆泌乳素（ Ｐ Ｒ Ｌ） 。结果： 镇痛组 Ｖ Ａ Ｓ 明显低于对照组（ Ｐ ＜ ０ ．０１） 。两组术后 Ｐ Ｒ Ｌ 均较术前明显升高（ Ｐ ＜ ０ ．０１） ，镇痛组术后 Ｐ Ｒ Ｌ 高于对照组，２４ｈ 具有显著性差异（ Ｐ ＜ ０ ．０５） ，４８ ｈ 具有非常显著性差异（ Ｐ ＜ ０ ．０１） 。相关分析表明镇痛组术后２４ ｈ 与４８ ｈ Ｖ Ａ Ｓ 评分均与血浆 Ｐ Ｒ Ｌ 浓度呈负相关（ Ｐ ＜ ０ ．０１） 。镇痛组初乳时间较对照组提前（ Ｐ ＜ ０ ．０５） 。婴儿体重增加明显高于对照组（ Ｐ ＜ ０ ．０５） 。镇痛组肠蠕动恢复时间明显快于对照组（ Ｐ ＜ ０ ．０１） ，镇痛组睡眠好， 但有３ 例一侧肢体麻木。两组宫缩无明显差异（ Ｐ ＞ ０ ．０５） 。结论：剖宫产术后布比卡因硬膜外镇痛能促进 Ｐ Ｒ Ｌ 分泌，增加母乳量及婴儿的?
Objective: To investigate the effect of continuous epidural injection of local anesthetic on prolactin and infant body weight after cesarean section. Methods: Sixty healthy full-term pregnant women were enrolled in this study. Elective cesarean section was performed under epidural anesthesia. The surgery was randomly divided into analgesia group and control group. Epidural analgesia was given in the analgesic group (n = 30) and injected with 0. 2% bupivacaine (2 ml / h) for 72h analgesia. The control group (n = 30) was removed epidural catheter. Plasma prolactin (P R L) was measured by radioimmunoassay in both groups. Results: VAS in analgesia group was significantly lower than that in control group (P <0.01). The postoperative P R L in both groups was significantly higher than that before operation (P <0.01). The postoperative P R L in the analgesic group was significantly higher than that in the control group (P <0.05) With a very significant difference (P <0 .01). Correlation analysis showed that the VAS score at 24 h and 48 h postoperatively in the analgesic group was negatively correlated with the plasma P R L concentration (P <0.01). Analgesia group colostrum earlier than the control group (P <0 .05). Infant weight gain was significantly higher than the control group (P <0 .05). Intestinal peristalsis pain relief group recovery time was significantly faster than the control group (P <0.01), analgesic sleep well, but three cases of numbness on one side. No significant difference between the two groups of contractions (P> 0.05). Conclusion: Bupivacaine epidural analgesia after cesarean delivery can promote the secretion of P R, increase the amount of breast milk and infant?