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急性心肌梗塞(AMI)心功能不全的发生机制与其它心脏病不同,它是冠脉急剧闭塞造成氧供求失衡的一种病理过程。因此矫正心肌耗氧的决定因素就成为治疗的关键。这些因素如下:(1)心律(2)前负荷(3)心肌收缩性(4)后负荷,末稍血管扩张剂的作用就在于降低心脏的前后负荷,而改善心泵功能。心泵功能(左室收缩功能)是由两种因素决定的。(1)左室心肌功能(前负荷、心肌收缩性、后负荷、心率)(2)末稍血管功
Acute myocardial infarction (AMI) The mechanism of cardiac insufficiency is different from other heart diseases. It is a pathological process of imbalance between supply and demand of oxygen caused by acute coronary occlusion. Therefore, the determinants of myocardial oxygen consumption correction has become the key to treatment. These factors are as follows: (1) heart rate (2) before the load (3) myocardial contractility (4) afterload, the role of terminal vasodilator is to reduce the heart before and after the load, and improve cardiac pump function. Cardiac pump function (left ventricular systolic function) is determined by two factors. (1) left ventricular myocardial function (preload, myocardial contractility, afterload, heart rate) (2) terminal vascular function