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Purpose: The concept of preventing the systemic absorption and cardiovascular and bronhopulmonary effects of topical timolol by impeding or redocing lacrimal drainage has not been studied yet. This investigation aimed to evaluate the potential preventive role of total punctal occlusion using collagen punctal plugs on the systemic adverse effect of topically applied timolol maleate 0.5%
Purpose: The concept of preventing the systemic absorption and cardiovascular and bronchial pulmonary effects of topical timolol by impeding or redocing lacrimal drainage has not been studied yet. This investigation aimed to evaluate the potential preventive role of total punctal occlusion using collagen punctal plugs on the systemic adverse effect of topically applied timolol maleate 0.5%