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儿童粗球孢子菌感染引起的喉梗阻很少见,但可危及生命。现报导1例接受免疫抑制剂治疗时的儿童球孢子菌病。病例 31个月的男婴,因日益加重的呼吸窘迫伴喘鸣2天收入当地医院,直接喉镜检查显示声门下水肿,会厌正常,经用肾上腺素、吸氧、支气管扩张药、抗生素及类固醇治疗,症状得到部分缓解,几天后再次发作而转院。患儿于生后18个月患激素依赖性肾病综合症,连续应用强的松治疗,在呼吸道症状发作前3个月,强的松剂量为60mg/m~2/d,于1个月前服环磷酰胺3mg/kg/d,在生后24个月至27个月间投以苯丁酸氮
Laryngeal obstruction caused by children with Coccidioidomycosis rare, but life-threatening. Is reported in 1 case of immunosuppressive agents in children with coccidioidomycosis. Case of 31-month-old boy, due to increasing respiratory distress with wheezing 2 days income at the local hospital, direct laryngoscopy showed subglottic edema, epiglottic normal, with epinephrine, oxygen, bronchodilators, antibiotics and steroids Treatment, symptoms were partially relieved, a few days after the attack and transfer to hospital. Children with steroid-dependent nephrotic syndrome were treated 18 months after birth with prednisone, and prednisone was prednisone 60 mg / m 2 / d three months prior to the onset of respiratory symptoms Serum cyclophosphamide 3mg / kg / d, after birth in the 24 months to 27 months to vote for phenylbutyrate nitrogen