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为寻找视网膜色素变性相关基因ＲＰ２所在的染色体位点，采用染色体Ｘｐ２１．１－ｐ１１．２区段的８个微卫星ＤＮＡ标记，对Ｘ－连锁ＲＰ（ＸＬＲＰ）家系进行连锁分析。家系ＪＧ的ＲＰ相关位点被定位于Ｘ染色体位标ＤＸＳ１０６８与ＤＸＳ１１２６之间。该区间可能是ＲＰ２所在部位，其跨度约５—７ｃＭ。可以认为该家系之视网膜色素变性病与ＲＰ２基因相关。该家系对寻找和克隆ＲＰ２基因非常有用。
In order to find the chromosomal loci where RP2 gene is involved in retinitis pigmentosa, eight microsatellite DNA markers of Xp21.1-p11.2 were used to analyze the X-linked RP (XLRP) pedigree. The RP-related locus of the family JG is mapped between the X-chromosome markers DXS1068 and DXS1126. The interval may be RP2 where the span of about 5-7cM. It can be considered that the pedigree of retinitis pigmentosa is associated with the RP2 gene. This family is very useful for finding and cloning the RP2 gene.