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目的 :观察纳络酮对不同原因引起的昏迷患儿在治疗中的价值。方法 :在胞二磷胆碱、脑活素、甘露醇、吸氧、病因及并发症的处理等常规治疗方法上 ,36例昏迷患儿加用纳络酮治疗 ,并与对照组 2 8例比较。结果 :治疗组意识及脑干功能恢复所需时间分别为 (1.2 4± 0 .76 )、(1.0 4± 0 .70 )天 ,较对照组的 (2 .85± 1.96 )、(2 .17± 1.5 5 )天明显减少 ,P均 <0 .0 1。结论 :昏迷患儿加用纳络酮疗效显著 ,可使意识及脑干功能恢复时间明显缩短 ,未见副作用。
Objective: To observe the value of naloxone in the treatment of children with coma caused by different causes. Methods: 36 cases of coma were treated with naloxone in routine treatment of citicoline, cerebrolysin, mannitol, oxygen, etiology and complications, and compared with 28 cases in control group Compare Results: The time required for recovery of consciousness and brainstem function in treatment group were (1.2 4 ± 0.76) days and (1.0 4 ± 0. 70 days) respectively, which were significantly higher than those in control group (2.85 ± 1.96) and (2.17 ± 1.5 5) days decreased significantly, P <0.01. Conclusion: The effect of naloxone on children with coma is significant, which can significantly shorten the recovery time of consciousness and brainstem function with no side effects.