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本实验用玻璃微电极细胞外记录尾核痛敏神经元电活动的方法,观察脑室注射 r—氨基丁酸(GABA)对尾核痛兴奋神经元(PEN)和痛抑制神经元(PIN)电活动的影响及腹腔注射 GABA 受体阻断剂印防己毒(Picro-toxin)对 GABA 的阻断效应。
In this study, we recorded the electrical activity of pain-sensitive neurons in the caudate nucleus by extracellular recording with glass microelectrode and observed the effects of intraventricular injection of gamma-aminobutyric acid (GABA) on pain nucleus-stimulating neurons (PEN) and pain-suppressing neurons (PIN) Activity and the blocking effect of intraperitoneal injection of GABA receptor antagonist Picro-toxin on GABA.