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本实验在40只大鼠经伺服零测压技术测定的肾脏微血管内压力分布及其ANP的作用均随血管树各段的口径变化而改变。分析小球前各段血管的压力降所占动脉总压降的比例得知:小叶间动脉占总压降的88％。肾小球毛细血管和出球小动脉亦具有较大的压力降。正常对照情况下,肾小球前血管内的压力分布与内径呈直线相关(r=0.869,n=65,P<0.01),其回归方程为平均压()=34.71±0.798×血管内径(D)。给ANP后肾小球前血管内的压力与内径仍呈直线相关(r=0.931,P<0.01),回归方程式为()=38.53+0.765D,其曲线右上移。本文结果提示,肾小球前微血管内压力分布与血管内径密切相关。小叶间动脉的阻力较大。
This experiment in 40 rats by servo zero pressure measurement of renal microvascular pressure distribution and the role of ANP with the vascular tree sections of the diameter changes. Analyze the proportion of the pressure drop of the blood vessels in each segment before the pellet, which is the total pressure drop of the artery, that is: 88% of the total pressure drop between the interlobular arteries. Glomerular capillaries and a small arteries also have a greater pressure drop. Under normal control, the pressure distribution in the pre-glomerular vessels was linearly correlated with the inner diameter (r = 0.869, n = 65, P <0.01). The regression equation was mean pressure () = 34.71 ± 0.798 × vessel diameter D). Before ANP, there was still a linear correlation between intra-glomerular pressure and internal diameter (r = 0.931, P <0.01). The regression equation was () = 38.53 + 0.765 D, and the curve shifted rightward. Our results suggest that the pre-glomerular capillary pressure distribution and vascular diameter are closely related. Interlobular arteries larger resistance.