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目的:探讨新疆维、汉族妇女原发性阴道癌相关危险因素的差异,为新疆维、汉族妇女原发性阴道癌的防治提供依据。方法:对1998年12月～2010年8月就诊于新疆医科大学附属肿瘤医院并诊断为原发性阴道癌的52例病历资料(汉族31例,维族21例)进行回顾性分析。结果:①52例患者平均年龄52.6岁,社会地位较低、文化程度以小学及文盲为主,年龄和文化程度民族之间无统计学差异;维吾尔族妇女以农民为主,职业在两民族之间有统计学差异。②18岁以前结婚12例(23.1%),均为维族,初婚年龄在两民族之间有统计学差异,生育次数3次及以上共28例(53.8%),两民族之间无统计学差异。③出现症状超过3个月就诊者29例(55.8%),两民族之间无统计学差异。④临床期别中汉族患者Ⅰ～Ⅱ期占本民族患者的48.4%,Ⅲ～Ⅳ期占52.6%,维族Ⅰ～Ⅱ期占本民族患者的42.9%,Ⅲ～Ⅳ期占57.1%,临床期别在两民族之间无统计学差异;鳞癌45例(86.5%),其中汉族24例、维族21例,腺癌6例(11.5%)均为汉族,腺鳞癌1例亦为汉族,病理类型在两民族之间有统计学差异;组织分化程度为中分化37例(71.2%),汉族22例、维族15例,无统计学差异。结论:新疆维、汉族妇女原发性阴道癌相关危险因素中文化程度、生育次数、就诊时间、临床分期、组织分化程度在两个民族女性间无统计学差异;职业、初婚年龄、病理类型有统计学差异。
Objective: To investigate the differences of risk factors related to primary vaginal cancer among Xinjiang Uygur and Han nationality women, and to provide basis for prevention and treatment of primary vaginal cancer in Xinjiang Uygur and Han women. Methods: A retrospective analysis of 52 cases (31 Han cases and 21 Uygurs) who were diagnosed as primary vaginal cancer at Cancer Hospital Affiliated to Xinjiang Medical University from December 1998 to August 2010 was retrospectively analyzed. Results: ① The average age of 52 patients was 52.6 years old, with a low social status. The educational level was mainly in primary schools and illiterates. There was no significant difference among ethnic groups in terms of age and educational level. Uighur women were dominated by peasants and occupations were between ethnic groups There are statistical differences. ② 12 married before the age of 18 (23.1%) were Uighurs. The age of first marriage was statistically different between the two ethnic groups. There were 28 cases (53.8%) with three or more births and no significant difference between the two ethnic groups. ③ There were 29 cases (55.8%) with symptoms more than 3 months, there was no significant difference between the two ethnic groups. ④ In the clinical stage, the Han and Han nationality patients accounted for 48.4% Ⅰ ~ Ⅱ of the nationalities, accounting for 52.6% of the patients in stage Ⅲ ~ Ⅳ, Uygur Ⅰ ~ Ⅱ accounted for 42.9% of the ethnic patients, Ⅲ ~ Ⅳ accounted for 57.1% 45 cases (86.5%) had squamous cell carcinoma, of which 24 cases were Han, 21 cases were Uygur, 6 cases were adenocarcinoma (11.5%) were Han nationality, 1 case was also adenocarcinoma of the Han nationality, There was a significant difference in the pathological types between the two ethnic groups. Tissue differentiation was moderately differentiated in 37 (71.2%), Han 22, and Uygur 15, with no significant difference. Conclusions: There is no significant difference in the level of education, birth frequency, visiting time, clinical stage and degree of tissue differentiation between Xinjiang Uygur and Han nationality women in the two ethnic groups. The occupation, the age at first marriage, the pathological types include Statistical differences.