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现在一般认为慢性淋巴细胞性白血病(CLL)的大多数病人是B一细胞起源的新生物疾病。若干组的研究已经证明在几乎所有的CLL病人的白血病性淋巴细胞上都有SlgM和IgD的存在;然而少数CLL病人的白血病性淋巴细胞上却有SIgG的存在。最近我们对患有B一细胞类型的65名病人的白血病淋巴细胞作了Slg的标记的研究。发现Slg的类型分布如下:这些病人的白血病细胞上,大多数的病人(61)有SlgM和SlgD;2个
It is now generally accepted that most patients with chronic lymphocytic leukemia (CLL) are neoplasms of the B-cell origin. Several groups of studies have demonstrated the presence of SlgM and IgD on leukemic lymphocytes in almost all CLL patients; however, the presence of SIgG is present on leukemic lymphocytes in a minority of CLL patients. We recently performed Slg labeling studies on leukemic lymphocytes from 65 patients with B-cell types. The distribution of Slg was found to be as follows: Most of the patients (61) had SlgM and SlgD on leukemic cells; two