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用732Fe+++型树脂为吸附剂,进行了木糖山梨糖混合溶液的分离试验。通过环状色谱床层中的物料衡算;取得了连续性方程的解,再以表征双组分混合液分离效果的参数定义为基础,假定了相平衡关系、返混规律和相间传质机制不变的情况下,用木糖或山梨糖色谱分离收集液的产率和分离度为目标函数,以进料浓度、进料液流量、冲洗液流量、床层高度和床层旋转速度等操作条件为变量进行估算,取得了一系列曲线和一些规津,可为连续环状色谱柱的工程放大,提供参考依据。
Using 732Fe +++ resin as adsorbent, the separation of xylose sorbitol solution was carried out. Based on the calculation of the material in the annular chromatography bed, the solution to the continuity equation was obtained. Based on the definition of the parameters that characterize the separation effect of the two-component mixture, the phase equilibrium, backmixing and interphase mass transfer mechanisms In the same condition, the yield and the resolution of the collected liquid are separated by using xylose or sorbose as the objective function, and the operation is carried out according to the feed concentration, the flow rate of the feed liquid, the flow rate of the rinse liquid, the height of the bed and the rotation speed of the bed The conditions for the variables are estimated, and a series of curves and some rules are obtained, which can provide a reference for the amplification of continuous annular columns.